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adversity ado adversities affliction afflict afflicts ail agitate ailed ails annoy annoyance annoys anxiety awkwardness bad thing bane besetment besiege bother bother break bore bothers bothers bug burdens burdens burden burden can of worms care care cares cares catastrophe check complaint complaints concern confuses confusion confuse consideration considerations corner crises crisis crunch cumber curse deep water depresses depress depression desperation devilry deviltry difficulty difficulty difficulty disagreed disagrees disagree discomfort discommode disconcert discourage discourages disoblige disorder disquiet disquiet dissatisfaction dissension distract distracts distress distress distress distresses distresses distresses disturb disturbs division dog dogging downsides downside drag drawbacks drawback dumps duties duty effort efforts embranglement embrangle embroil exercise exertion extremity extremities force fracas fret friction gall gnaw grief grievances grievance grind harass harassment hardships hardship harry hassle hate hates haunt headache hitch holdup hornet's nest hurt ill ills incommode incommodiousness incommodity interfere irk irritant jam lade load load loss matter mayhem menace millstone mind mindfulness misfortune misfortune/mishap misfortunes misfortunes misplacement mishaps molest muddle nuisance obstruction oppress pain pain perturb pest plagues plague plight predicament pressure pressures preyed on prey on problem problems put out quagmire repellence repellency repugnancy riot riots row ruffle rub scrape setback setbacks shenanigans soreness sorrow spots spot squall strain strains stressor tasks task thundercloud topsy-turviness torment torment traumatize traumatizing traumatized tribulation tries try turmoil uncertainties uncertainty undoing uneasiness unease unfortunateness unluckiness unpleasantness unrest unsettle untowardness upset vexation vexes vex visitation visited visit visits weigh down woe woes work worry wound worries wounds